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????height=$this.next().height(); ????$(this).css("height",height); var obj = $(o); var val = obj.text(); if(val == '' || val == null || val == undefined){ $(this).addClass('none'); }else{ $(this).removeClass('none'); } }); $(".proshowParameter table td").each(function?(i,o){ var obj = $(o); var val = obj.text(); if(val == '' || val == null || val == undefined){ $(this).addClass('none'); }else{ $(this).removeClass('none'); } }); } </script> <section class="proshowParameter"> <table style=" margin-bottom:20px;"> <tbody> <tr><th>品牌</th><td>Beadstar-mPlex</td><th>供貨周期</th><td>一周</td></tr><tr><th>主要用途</th><td>多種細(xì)胞因子檢測(cè)</td> <th></th><td></td></tr> </tbody> </table> </section></div> <div id="miq7aop" class="c_detail_wrap"> <p style="box-sizing: inherit; margin-top: 0px; margin-bottom: 1rem; color: rgb(42, 51, 60); line-height: 1.5em;"><br/></p><div style="text-align: left; margin-bottom: 10px;"><p style="text-align: left; margin-bottom: 10px;"><span style="color: rgb(51, 51, 51); font-family: " helvetica="" font-size:="" background-color:="">Th2細(xì)胞介導(dǎo)針對(duì)細(xì)胞外寄生蟲(chóng)、細(xì)菌、過(guò)敏原和毒素的體液或抗體介導(dǎo)的免疫反應(yīng)的活化和維持。Th2細(xì)胞通過(guò)生成各種細(xì)胞因子來(lái)介導(dǎo)這些功能。這些細(xì)胞因子負(fù)責(zé)促進(jìn)抗體合成、活化嗜酸性粒細(xì)胞和抑制多種巨噬細(xì)胞功能，從而提供獨(dú)立于吞噬細(xì)胞的保護(hù)反應(yīng)。這些細(xì)胞因子也會(huì)抵消Th1反應(yīng)，使Th2接受IL-4的刺激活化。在功能上，由于細(xì)胞因子受體在多種細(xì)胞類型中廣泛表達(dá)，因此Th2細(xì)胞因子對(duì)體內(nèi)的許多細(xì)胞類型都有影響。Th2細(xì)胞刺激并募集免疫細(xì)胞的特定亞群，例如嗜酸性粒細(xì)胞和嗜堿性粒細(xì)胞，使其到達(dá)感染部位或?qū)?dǎo)致組織嗜酸性粒細(xì)胞增多和肥大細(xì)胞增生的過(guò)敏原或毒素作出反應(yīng)。其誘導(dǎo)粘液生成、杯狀細(xì)胞化生和氣道高反應(yīng)性。Th2細(xì)胞也調(diào)控B細(xì)胞IgE類別轉(zhuǎn)換。由于Th2細(xì)胞對(duì)抗體生成和過(guò)敏反應(yīng)的影響，Th2細(xì)胞的過(guò)度活化似乎是過(guò)敏（1型，速發(fā)型超敏反應(yīng)）、自身免疫反應(yīng)（如慢性移植物抗宿主病、進(jìn)行性系統(tǒng)性硬化癥和系統(tǒng)性紅斑狼瘡）惡化的原因。此外，Th2細(xì)胞也被認(rèn)為是導(dǎo)致哮喘和其他過(guò)敏性炎癥疾病惡化的原因。有趣的是，Th2細(xì)胞還生成具有抗腫瘤作用的生長(zhǎng)因子雙調(diào)蛋白和IL-24。</span></p></div><p style="box-sizing: inherit; margin-top: 0px; margin-bottom: 1rem; color: rgb(42, 51, 60); font-family: " segoe="" lucida="" microsoft="" droid="" wenquanyi="" micro="" hiragino="" sans="" gb="" white-space:="" background-color:="" text-indent:="" line-height:=""><span style="font-size: 16px;"><span style="box-sizing: inherit; color: rgb(0, 112, 192);">Beadstar-mPlex Th2多細(xì)胞因子檢測(cè)試劑盒</span></span></p><p style="box-sizing: inherit; color: rgb(42, 51, 60); font-family: " segoe="" lucida="" microsoft="" droid="" wenquanyi="" micro="" hiragino="" sans="" gb="" white-space:="" background-color:="" text-indent:="" line-height:=""><span style="font-family: " times="" new="" font-size:=""><span style="font-family: " times="" new="" box-sizing:="" text-indent:="">檢測(cè)細(xì)胞因子：</span><span style="font-family: " times="" new="" box-sizing:="" text-indent:=""><span style="color: rgb(25, 25, 25); font-family: " pingfang="" font-size:="" background-color:="">IL-4、<span style="color: rgb(25, 25, 25);">IL-5、</span>IL-10</span></span></span></p><p style="box-sizing: inherit; color: rgb(42, 51, 60); font-family: " segoe="" lucida="" microsoft="" droid="" wenquanyi="" micro="" hiragino="" sans="" gb="" white-space:="" background-color:="" text-indent:="" line-height:=""><br/></p><p style="box-sizing: inherit; color: rgb(42, 51, 60); font-family: " segoe="" lucida="" microsoft="" droid="" wenquanyi="" micro="" hiragino="" sans="" gb="" white-space:="" background-color:="" text-indent:="" line-height:=""><span style="box-sizing: inherit; color: rgb(0, 0, 0); font-family: " times="" new="" font-size:="">所需樣本量：血清（5-10 微升）；細(xì)胞上清（25-50 微升）</span></p><p style="box-sizing: inherit; color: rgb(42, 51, 60); font-family: " segoe="" lucida="" microsoft="" droid="" wenquanyi="" micro="" hiragino="" sans="" gb="" white-space:="" background-color:="" text-indent:="" line-height:=""><span style="box-sizing: inherit; color: rgb(0, 0, 0); font-family: " times="" new="" font-size:="">適應(yīng)機(jī)型：通用性強(qiáng)，普通流式機(jī)型均可檢測(cè)</span></p><p style="box-sizing: inherit; margin-top: 0px; margin-bottom: 1rem; color: rgb(42, 51, 60); font-family: " segoe="" lucida="" microsoft="" droid="" wenquanyi="" micro="" hiragino="" sans="" gb="" white-space:="" background-color:="" text-indent:="" line-height:=""><br/></p><p style="box-sizing: inherit; margin-top: 0px; margin-bottom: 1rem; color: rgb(42, 51, 60); line-height: 1.5em;"><span style="box-sizing: inherit; color: rgb(0, 0, 0); font-family: arial, helvetica, sans-serif;"><br/></span></p><p style="box-sizing: inherit; margin-top: 0px; margin-bottom: 1rem; color: rgb(42, 51, 60); line-height: 2em;"><span style="box-sizing: inherit; color: rgb(0, 0, 0); font-family: arial, helvetica, sans-serif;"><span style="color: rgb(0, 112, 192); font-size: 16px;">Beadstar-mPlex Th2多細(xì)胞因子檢測(cè)試</span></span><span style="box-sizing: inherit; font-family: arial, helvetica, sans-serif; color: rgb(0, 112, 192); font-size: 16px;">劑盒檢測(cè)原理</span></p><p style="box-sizing: inherit; margin-top: 0px; margin-bottom: 1rem; color: rgb(42, 51, 60); line-height: 2em;"><span style="box-sizing: inherit; color: rgb(0, 0, 0); font-family: arial, helvetica, sans-serif;">本試劑盒以流式分析為基礎(chǔ)，檢測(cè)原理如圖1所示，在特定熒光編碼的微球上分別連接對(duì)應(yīng)的人細(xì)胞因子抗體用于捕獲溶液中的細(xì)胞因子。當(dāng)檢測(cè)樣品中存在這些細(xì)胞因子時(shí)，這些連接熒光編碼微球的捕獲抗體將會(huì)與其結(jié)合，最后通過(guò)加入藻紅蛋白（PE）標(biāo)記的特異性檢測(cè)抗體，形成微球連接的捕獲抗體-抗原-PE標(biāo)記的檢測(cè)抗體復(fù)合物。在流式細(xì)胞儀藻藍(lán)蛋白（APC）和藻藍(lán)蛋白-Cy7（APC-Cy7）通道下，12群微球被識(shí)別并用于判定抗原（圖2）；在流式細(xì)胞儀PE通道下，微球體上PE的熒光強(qiáng)度與樣本中各被檢測(cè)物的濃度呈正相關(guān)，各校準(zhǔn)品與其對(duì)應(yīng)的熒光信號(hào)可擬合成濃度—熒光強(qiáng)度標(biāo)準(zhǔn)曲線，通過(guò)曲線方程可計(jì)算出各抗原的濃度。</span></p><p style="box-sizing: inherit; margin-top: 0px; margin-bottom: 1rem; color: rgb(42, 51, 60); line-height: 1.5em;"><br/></p><p style="text-align: center"><img src="https://img64.chem17.com/gxhpic_3069c9eba7/d6168c174cc86a73105708f7583645a717359fc6216e98328c3ad75697f64901b7a25cab51fc60e8.jpg" style="width:800px;"/></p><p style="box-sizing: inherit; margin-top: 0px; margin-bottom: 1rem; color: rgb(42, 51, 60); line-height: 1.5em; text-align: center;">圖1流式熒光法高通量檢測(cè)細(xì)胞因子原理示意圖（以6細(xì)胞因子檢測(cè)為例）</p><p style="text-align: center"><img src="https://img69.chem17.com/gxhpic_3069c9eba7/d6168c174cc86a73105708f7583645a7507bae512e0ea385b7c4fa5b875b59bfd9b3577456c7568a.png" style="width:800px;"/></p><p style="text-align: center;">圖2. 各微球?qū)?yīng)的細(xì)胞因子</p><p style="box-sizing: inherit; margin-top: 0px; margin-bottom: 1rem; color: rgb(42, 51, 60); line-height: 1.5em;"><br/></p><p style="box-sizing: inherit; margin-top: 8px; margin-bottom: 1rem; color: rgb(42, 51, 60); line-height: 1.5em;"><span style="font-family: arial, helvetica, sans-serif;"><strong style="box-sizing: inherit;"><span style="box-sizing: inherit; color: rgb(68, 114, 196);">我們的優(yōu)勢(shì):</span></strong></span></p><p style="box-sizing: inherit; margin-top: 0px; margin-bottom: 1rem; color: rgb(42, 51, 60); line-height: 1.5em;"><span style="font-family: arial, helvetica, sans-serif;"><strong><span 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